The ankle Squeeze Test assesses whether compressing the tibia and fibula together in the lower leg reproduces pain at the distal syndesmosis. It is commonly used when high ankle sprain is suspected. A 2021 systematic review of ankle syndesmosis clinical tests found that test accuracy varies and that clustering history, palpation and clinical tests is preferred over relying on one test alone.
A client reports pain above the ankle after a twisting injury, external rotation mechanism, tackle or ski fall. They may have difficulty pushing off, pain when rotating the ankle or tenderness over the distal tibiofibular joint.
The Squeeze Test can help assess whether proximal tibia-fibula compression reproduces distal syndesmosis pain. It should be interpreted alongside Kleiger’s Test, syndesmosis palpation, weight-bearing ability, swelling, mechanism of injury and imaging/referral decisions.
Test name: Squeeze Test
Body region: Ankle syndesmosis, distal tibiofibular joint
Purpose: Assess distal syndesmosis pain response to tibia-fibula compression
Positive finding: Familiar pain at the distal syndesmosis or ankle during lower-leg compression
Negative finding: No familiar distal syndesmosis pain during compression
Best used with: Kleiger’s Test, syndesmosis palpation, dorsiflexion-external rotation reasoning, weight-bearing tolerance and imaging/referral when indicated
Key limitation: It does not confirm syndesmosis injury on its own
The Squeeze Test is a clinical test for suspected syndesmosis injury. The professional compresses the tibia and fibula together in the mid or upper lower leg. A positive response is pain felt distally near the ankle syndesmosis rather than simply pain where the leg is squeezed.
The test is used when high ankle sprain or syndesmotic ligament injury is part of the assessment reasoning.
It may be relevant after external rotation injuries, contact sport, skiing, landing injuries, falls, twisting trauma or ankle pain located above the joint line.
The test assesses symptom response at the distal syndesmosis when the tibia and fibula are compressed proximally. It does not directly visualise ligament injury or grade instability.
Pain at the squeeze site alone is not the same as a positive syndesmosis test.
This test may be useful for field-sport athletes, skiers, runners, dancers and clients with suspected high ankle sprain or pain above the ankle after trauma.
Use when syndesmosis injury is suspected and compression can be applied safely.
Use caution with suspected fracture, severe swelling, severe pain, acute high-energy trauma, obvious deformity, inability to weight bear, recent surgery or significant calf pain.
Do not perform aggressive compression if fracture or serious injury is suspected.
Treatment table or chair
Pain scale
Measurz recording workflow
Optional comparison-side notes
Optional referral notes
Position the client sitting or supine with the lower leg relaxed.
The knee may be slightly flexed or relaxed depending on the setup.
Stand or sit beside the lower leg.
Place both hands around the tibia and fibula in the mid or upper calf region.
Support the limb so the client can remain relaxed.
Compress the tibia and fibula together gradually.
Ask the client to report where pain is felt, whether it occurs distally at the ankle, and whether it matches their usual symptoms.
A positive Squeeze Test is familiar pain at the distal syndesmosis or ankle during compression.
A negative finding is no familiar distal syndesmosis pain during compression.
Stop if pain is sharp, calf pain is severe, neurological symptoms occur or compression is not tolerated.
Record pain location clearly. Local calf pain alone should not be interpreted as a positive syndesmosis test.
A positive Squeeze Test may increase suspicion of syndesmosis injury when compression of the tibia and fibula reproduces familiar pain at the distal syndesmosis. It is more meaningful when combined with an external rotation mechanism, syndesmosis tenderness, difficulty weight bearing and a positive Kleiger’s/external rotation stress test.
A negative test does not exclude syndesmosis injury. Some high ankle sprains may be missed if testing is performed too early, too gently, or if symptoms are mainly load-specific.
A 2021 systematic review summarised diagnostic accuracy of clinical tests for ankle syndesmosis injury and found that no single clinical test should be used in isolation. The review included studies comparing clinical examination with arthroscopy, MRI or ultrasound and recommended test clustering to improve diagnostic reasoning.
Condition or presentation: suspected ankle syndesmosis injury/high ankle sprain
Population: people with suspected syndesmotic ligament injury
Test variation: tibia-fibula squeeze test
Reference standard: arthroscopy, MRI or ultrasound depending on study
Sensitivity: variable and not suitable for one universal value here
Specificity: variable depending on study and test definition
Positive likelihood ratio: varies by study
Negative likelihood ratio: varies by study
Key limitations: variable squeeze location, force, injury severity, reference standards and timing after injury
A separate systematic review on syndesmosis injury diagnostics reported that external rotation stress test and squeeze test were among the most commonly applied clinical tests in surgical decision-making studies.
Reliability depends on squeeze location, compression force, symptom criteria and whether distal pain is distinguished from local calf discomfort. Earlier evidence has reported better intra-rater reliability for the squeeze test than inter-rater reliability in some syndesmosis testing contexts.
Validity improves when the test is interpreted with mechanism, palpation, external rotation stress testing and imaging/referral when appropriate.
Common errors include compressing too aggressively, interpreting local calf discomfort as positive, not recording pain location, relying on the test alone and ignoring inability to weight bear or fracture risk.
Limitations include variable force, acute pain guarding, symptom overlap and incomplete stand-alone diagnostic certainty.
Use the Squeeze Test to document distal syndesmosis pain response and guide decisions about load modification, referral, imaging and return-to-sport progression.
Record test name, side tested, result, squeeze location, compression force, pain score, pain location, distal syndesmosis pain yes/no, symptom familiarity, comparison side, swelling, weight-bearing ability, confidence in result and reason for stopping.
Add related findings such as Kleiger’s Test, syndesmosis palpation, ankle dorsiflexion ROM, eversion stress, hop testing, sport mechanism and referral notes.
Kleiger’s Test
Eversion Stress Test
Anterior Drawer of the Ankle
Talar Tilt Test
Ankle Dorsiflexion Test
Hop Tests
Single Leg Calf Raise
Balance and Proprioception Tests
It assesses whether tibia-fibula compression reproduces pain at the distal ankle syndesmosis.
A positive result is familiar distal syndesmosis or ankle pain during lower-leg compression.
Not usually. The key finding is distal ankle or syndesmosis pain, not local squeeze discomfort.
No. It may support suspicion but does not confirm syndesmosis injury on its own.
Record squeeze location, pain location, pain score, distal symptoms, comparison side and related syndesmosis findings.
The Squeeze Test is used for suspected syndesmosis injury.
Distal ankle pain is more meaningful than local calf discomfort.
No single syndesmosis test should be used alone.
Use it with Kleiger’s Test, palpation, history and weight-bearing findings.
Measurz should capture squeeze location, distal pain and comparison findings.
Netterström-Wedin, F., & Bleakley, C. (2021). Diagnostic accuracy of clinical tests assessing ligamentous injury of the ankle syndesmosis: A systematic review with meta-analysis. Physical Therapy in Sport, 49, 214–226.
Wever, K. E., et al. (2022). A systematic review of studies on the diagnostics and classification of syndesmotic injury. Journal details need verification.